Gurjeva  Valentina Andreevna   (doctor of medical Sciences, Professor, Altai state medical University)
                
            
            
                Shadeeva  Julia Alexandrovna   (assistant, Altai state medical University )
                
            
            
                Сhugunova  Tatjana Nikolaevna   (for pediatric care deputy chief medical officer. Altai Perinatal Center)
                
            
            
    
        
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                        |  | The aim of the study was to investigate the frequency and severity of risk factors of premature rupture of membranes (PROM) at a gestational age of 22-34 weeks. The study is built on the basis of retrospective analysis of case – control. The main group consisted of 205 patients, a pregnancy which was complicated by the PROM. The control group included 107 patients who gave birth at term pregnancy. The factors that increase the risk of PROM is proved: age of pregnant women older than 35 years, illegitimate pregnancy, premature births, history of abortions, multiple pregnancy, acute infections, Smoking during pregnancy, isthmic-cervical insufficiency. Thus, knowledge of risk factors is the possibility of predicting the risk of PROM in terms of 22-34 weeks of gestation and to prevent taking into account controlled fac-tors.  Keywords:Preterm labor, premature rupture of membranes, premature pregnancy, risk factors. |  | 
        
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                        | Citation link: Gurjeva  V. A., Shadeeva  J. A., Сhugunova  T. N. Risk factors of premature rupture of membranes at gestational age of 22-34 weeks // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2016. -№08. -С. 84-92
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