Ruhlyada  Nikolaj Nikolaevich   (MD, PhD, Dr Med Sci, professor, Head of the Department of Obstetrics and Gynecology, St. Petersburg State Pediatric Medical University Ministry of Health of the Russian Federation )
                
            
            
                Vinnikova   Simona Viktorovna   (Researcher of the Gynecology Department of the State Medical Institution "St. Petersburg Research Institute" of Ambulance named after I. I. Janelidze)
                
            
            
    
        
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                        |  | Undeveloped pregnancy occurs in 10.0-20.0%, and in 55.6% of pregnancies at a later date, the cause is urogenital infectious diseases. The aim of our study was to evaluate the recurrence rate of vaginal and colon dysbiosis in women with a history of undeveloped pregnancy after the use of pro-, meta- and prebiotic drugs. For 12 months, the state of the vaginal and intestinal microbiome was monitored in women with a history of undeveloped pregnancy after therapy. Combination therapy (combined antimicrobial drug + combined biotic drugs) contributes to the complete elimination of dysbiosis in the studied environments. Repeated cases of dysbiotic disorders of the vaginal and intestinal microbiome were detected in 12.0% of patients with combined use of antibacterial and biotic drugs. At the same time, no recurrence of dysbiotic disorders in the studied media was detected in 68.0%. Keywords:undeveloped pregnancy, microbiome, vagina, colon, dysbiosis. |  | 
        
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                        | Citation link: Ruhlyada  N. N., Vinnikova   S. V. DYNAMIC MONITORING OF THE STATE OF THE VAGINAL AND INTESTINAL MICROBIOME IN WOMEN WITH A HISTORY OF UNDEVELOPED PREGNANCY // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2024. -№08. -С. 191-194 DOI 10.37882/2223-2966.2024.8.27
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