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THE USE OF HYPERBARIC OXYGENATION IN THE COMPLEX THERAPY OF DIABETIC FOOT

Vvedenskaya Irina Petrovna  (Samara State Medical University of the Ministry of Health of the Russian Federation Candidate of Medical Sciences, Assistant )

Kazennov Dmitry Alexandrovich  (GBUZ SO "Samara city polyclinic No. 4" general practitioner )

Kaluzhskikh Ekaterina Alexandrovna  (GBUZ SO "Samara city polyclinic" general practitioner )

Vvedensky Vasily Yurievich  (GBUZ SB " Otradnenskaya City Hospital" head of the department)

The article is devoted to the study of the effectiveness of hyperbaric oxygenation (HBO) in the complex therapy of diabetic foot syndrome (DFS). A prospective randomized controlled trial was conducted on a sample of 60 patients with stage II-IV diabetes mellitus according to Wagner. The main group (n=30) received standard therapy in combination with a course of HBO (2 ATA, 60 min, 10 sessions). In the control group (n=30), only standard therapy was performed. The dynamics of the wound process, microcirculation, and markers of inflammation were evaluated. The results showed a statistically significant improvement in wound healing (area, depth, rate of epithelialization) in the main group compared with the control group (p<0.05). There was a significant increase in transcutaneous oxygen voltage (TcPO2) and a decrease in the level of CRP and IL-6 in the HBO group (p<0.05). The frequency of high amputations was 6.7% in the main group versus 20% in the control (p<0.05). The data obtained indicate the expediency of including HBO in the complex of therapeutic measures for VDS, which helps to accelerate reparative processes, improve microcirculation and reduce the risk of amputations.

Keywords:diabetic foot syndrome, hyperbaric oxygenation, wound healing, microcirculation, transcutaneous oxygen tension, high amputationsmunotherapy
 

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Citation link:
Vvedenskaya I. P., Kazennov D. A., Kaluzhskikh E. A., Vvedensky V. Y. THE USE OF HYPERBARIC OXYGENATION IN THE COMPLEX THERAPY OF DIABETIC FOOT // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2024. -№11/2. -С. 149-154 DOI 10.37882/2223-2966.2024.11-2.08
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