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THE EFFECT OF POLYPHENOLIC COMPOUNDS ON THE PATHOGENESIS OF DIABETES MELLITUS: MECHANISMS OF ACTION AND PROSPECTS FOR USE

Saatashvili Zoya   (V. I. Vernadsky Crimean Federal University (Simferopol))

Saatashvili Sopia   (V. I. Vernadsky Crimean Federal University (Simferopol))

Ziyadinov Marlen Ruslanovich  (V. I. Vernadsky Crimean Federal University (Simferopol))

Diabetes mellitus (DM) is one of the most significant global public health challenges, characterized by a chronic increase in blood glucose levels. This endocrine pathology is associated with long-term complications, a decrease in quality of life and an increase in mortality. In recent decades, the scientific community has been actively exploring the possibilities of correcting the pathogenesis of diabetes, among which special attention is paid to the study of bioactive substances of natural origin, in particular, polyphenolic compounds. This article is devoted to a comprehensive review of current data on the mechanisms of action of polyphenolic compounds on the pathogenesis of diabetes mellitus and the prospects for their use in medical practice.

Keywords:diabetes mellitus, polyphenols, insulin, inflammation, cytokines
 

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Citation link:
Saatashvili Z. , Saatashvili S. , Ziyadinov M. R. THE EFFECT OF POLYPHENOLIC COMPOUNDS ON THE PATHOGENESIS OF DIABETES MELLITUS: MECHANISMS OF ACTION AND PROSPECTS FOR USE // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2024. -№11/2. -С. 208-210 DOI 10.37882/2223-2966.2024.11-2.27
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