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POSSIBILITIES OF USING MICROVESICLES OF MESENCHYMAL STEM CELLS

Khafizov Irek R.  (Candidate of Medical Sciences, Associate Professor, Department of Dentistry and Implantology, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) )

Rogunov Ilya V.  (Teacher, Department of Dentistry and Implantology, Institute of Fundamental Medicine and Biology, Kazan (Volga Region))

Agliullina Dilyara А.  (Institute of Fundamental Medicine and Biology, Kazan (Volga Region))

Kurbanova Elvina А.  (Institute of Fundamental Medicine and Biology, Kazan (Volga Region))

The article examines the use of extracellular microvesicles (EMVs) in various diseases derived from mesenchymal stem cells taken from several tissue sources, both from humans and animals. EMVs are used for kidney diseases, myocardial infarction, and other tissue damage. The inclusion of EMV MSCs in biomaterials is a necessary component, since microvesicles contribute to the treatment of pathologies associated with metabolism, regeneration, and the formation of bone tissue. Cell-free therapy based on the use of EMVs from MSCs has advantages over others, such as ease of collection, handling, and storage, lower carcinogenicity potential, and greater versatility in dose and efficacy assessment, unlike traditional treatment methods. Aims: to study the use of extracellular microvesicles of mesenchymal stem cells in modern medicine. Materials and methods: a literature search was conducted on the methods and methods of the effect of EMV MSC on pathological processes occurring in the human body. Search criteria: review and scientific articles (in Russian and English), published no later than 2015, by keywords: extracellular microvesicles, mesenchymal stem cells, cancer, regeneration, biomaterials, bone. Conclusion: the conducted literary analysis has identified the main common methods of using EMV MSC in modern medicine.

Keywords:extracellular microvesicles, mesenchymal stem cells, cancer, regeneration, biomaterials, bone.

 

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Citation link:
Khafizov I. R., Rogunov I. V., Agliullina D. А., Kurbanova E. А. POSSIBILITIES OF USING MICROVESICLES OF MESENCHYMAL STEM CELLS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2024. -№11/2. -С. 38-42 DOI 10.37882/2223-2966.2024.11-2.34
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