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FEATURES OF THE MICROBIOTA OF THE UTERINE CAVITY IN WOMEN WITH ENDOMETRIAL HYPERPLASTIC PROCESSES

Kotelnikova Nadezhda Alexandrovna  (Applicant for the Department of Ultrasound Diagnostics, IPO SamSMU Samara State Medical University Russian Federation, Samara )

Balter Regina Borisovna  (Candidate of Medical Sciences, Professor Head of the Department of Ultrasound Diagnostics, IPO SamSMU Samara State Medical University Russian Federation, Samara )

Tselkovich Lyudmila Savelyevna  (Doctor of Medical Sciences Professor of the Department of Ultrasound Diagnostics, IPO SamSMU Samara State Medical University Russian Federation, Samara )

Ivanova Tatiana Vladimirovna  (Candidate of Medical Sciences Associate Professor, Department of Ultrasound Diagnostics, IPO SamSMU Samara State Medical University Russian Federation, Samara )

Ilchenko Olesya Andreevna  (Ph.D., Assistant of the Department of Ultrasound Diagnostics, IPO SamSMU Samara State Medical University Doctor - obstetrician-gynecologist GBUZ SO SGP № 3 Russian Federation, Samara )

Pugacheva Tatiana Alexandrovna  (Candidate of medical sciences Assistant of the ultrasonic diagnostics department of IPO SamSMU Samara State Medical University Russian Federation, Samara )

The microbiota of the uterine cavity and its influence on the prognosis of malignization of atypical hyperplasia in women with simple and atypical endometrial hyperplasia are considered. Comparative analysis and histologic verification of the diagnosis in 216 patients were performed. The results were processed in the medical statistics program MedCalc, version 15.2. Pseudomonas aeruginosa and Parabacteroides bacteria were most frequently detected in patients with hyperplasia without atypia, and Atopobium, Capnocytophaga and Staphilococcus epidermidis bacteria in women with atypical hyperplasia. The frequency of malignization of hyperplasia with atypia was found to correlate with the presence of normal microflora in the uterine cavity in concentrations exceeding normal values.

Keywords:simple endometrial hyperplasia, atypical endometrial hyperplasia, uterine cavity microbiota, endometritis, malignancy

 

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Citation link:
Kotelnikova N. A., Balter R. B., Tselkovich L. S., Ivanova T. V., Ilchenko O. A., Pugacheva T. A. FEATURES OF THE MICROBIOTA OF THE UTERINE CAVITY IN WOMEN WITH ENDOMETRIAL HYPERPLASTIC PROCESSES // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2024. -№11. -С. 209-213 DOI 10.37882/2223-2966.2024.11.16
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