Karasev Ivan Aleksandrovic (Candidate of Medical Sciences, Associate Professor, Head of the Endoscopy Department, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, Moscow
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The study presents an analysis of the colonic microbiome and stool microbiome in patients with adenomas and colorectal cancer. The microbiota is critical in the pathogenesis of sporadic colorectal cancer, as evidenced by the identification of certain microorganisms associated with different stages of precancerous lesions. The microbiome was investigated in correlation with the type, localization and risk of malignization of neoplasms. The study methodology included 16S rRNA sequencing and data analysis using modern bioinformatics tools. The results demonstrate that the microbiome may be associated with the morphologic type and potential of neoplasms, which holds promise for the development of new methods for colorectal cancer diagnosis and prevention.
Keywords:colorectal cancer, intestinal microbiome, adenomas, malignization, sequencing
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Citation link:
Karasev I. A. ANALYSIS OF COLONIC AND STOOL MICROBIAL COMPOSITION SAMPLES FROM PATIENTS WITH ADENOMAS AND COLORECTAL CANCER // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2024. -№11. -С. 202-208 DOI 10.37882/2223-2966.2024.11.13 |
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