Akhmetzyanov Foat Shaikhutdinovich (MD, Professor, Head of the Department of Oncology, Radiation Diagnostics and Radiation Therapy of th in Kazan State Medical University of the Russian Federation; Head of the surgical clinic LDK2 GAUZ "Republican Clinical Oncological Dispensary" of the Republic of Tatarstan, Kazan)
Ankhimova Lyubov Evgenievna (graduate student of the Department of Oncology, Radiation Diagnostics and Radiation therapy of the in Kazan State Medical University of the Russian Federation; oncologist GAUZ "GKB No. 7 MZ RT named after M.N. Sadykov », Kazan )
Akhmetzyanova Rezeda Foatovna (an oncologist of the oncology department No. 11 of the GAUZ “Republican Clinical Oncological Dispensary” of the Republic of Tatarstan, Kazan)
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Breast cancer (BC) is a heterogeneous disease requiring an individualized approach to treatment. Non-combinatorial methods, such as surgical intervention combined with hormone therapy, play an essential role in controlling early stages of the disease. This article presents a review of key studies and their results in the field of non-combinatorial therapy for BC without postoperative radiation therapy.
We conducted a retrospective analysis of medical records of patients with pT(is,1,2)N0-1M0 treated at the Republic Clinical Oncology Dispensary from 2012 to 2022. Our findings demonstrated that in the case of small tumors measuring up to 1 cm in diameter and undergoing organ-saving surgery (OSO) with classic axillary lymphadenectomy (ALAE), consideration may be given to omitting postoperative radiation therapy (PORT) in patients over 55 years of age with estrogen receptor (ER) and/or progesterone receptor (PR) positivity and negative HER2, followed by prolonged hormone therapy. Results from patient surveys using the SF-36 scale indicated an improvement in quality of life and cosmetic outcomes.
Keywords:breast cancer, organ-preserving surgeries, radiation therapy.
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Citation link:
Akhmetzyanov F. S., Ankhimova L. E., Akhmetzyanova R. F. LOCAL RECURRENCE RATES OF BREAST CANCER pT (IS,1,2)N0-1M0 AND THEIR DEPENDENCE ON DIFFERENT TREATMENT MODALITIES // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2025. -№04. -С. 178-183 DOI 10.37882/2223-2966.2025.04.01 |
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