Bugero Nina Vladimirovna (Doctor of Biological Sciences,
Professor of the Department of Fundamental Medicine and General Pathology
Federal State Budgetary Educational Institution of Higher Education "Pskov State University"
)
Aleksandrova Svetlana Mikhailovna (PhD, Associate Professor of the Department of Chemistry and Natural Science Education
Federal State Budgetary Educational Institution of Higher Education "Pskov State University"
)
Titova Anna Aleksandrovna (Senior Lecturer of the Department of Fundamental Medicine and General Pathology,
Pskov State University
)
Yakimova Darya Vyacheslavovna (Federal State Budgetary Educational Institution of Higher Education "Pskov State University")
Pavlova Elena Vladimirovna (PhD, Associate Professor of the Department of Chemistry and Natural Science Education
Federal State Budgetary Educational Institution of Higher Education "Pskov State University"
)
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During the development and application of diagnostic methods for biochemical parameters: alpha-amylase, glucose and total bilirubin in two groups of people, the following results were obtained: when determining the activity of alpha-amylase, an increased level of activity of this enzyme was shown in both forms of pancreatitis: in acute pancreatitis, the indicators exceed normal values by 3.95 times, in chronic pancreatitis they did not exceed the norm. When determining the glucose level in acute pancreatitis, the readings were 1.8 times higher than normal, in chronic pancreatitis - 1.2 times. When determining bilirubin in the blood, an increased level of its total value was noted in patients with chronic pancreatitis - 1.4 times. The study showed that patients of different age categories with acute and chronic pancreatitis have differences in biochemical blood parameters. Perhaps, age can affect the severity of the disease and the response to treatment. Further research is needed to better understand the effect of age on biochemical processes in pancreatitis. The study data showed differences in the distribution of patients by age and gender depending on the form of pancreatitis. Women older than working age are more susceptible to chronic pancreatitis, while in men this applies to the acute form of the disease. The study revealed that gallstone disease is observed mainly in women who were diagnosed with chronic pancreatitis.
Keywords:pancreatitis, biochemistry, gallstone disease, alpha-amylase, glucose, bilirubin.
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Citation link:
Bugero N. V., Aleksandrova S. M., Titova A. A., Yakimova D. V., Pavlova E. V. MODERN CLINICAL BIOCHEMISTRY POSSIBILITIES IN LABORATORY DIAGNOSTICS OF ACUTE AND CHRONIC PANCREATITIS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2025. -№08. -С. 12-18 DOI 10.37882/2223-2966.2025.08.04 |
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