Krotov Gleb Alexandrovich (Applicant
A.S. Loginov Moscow Clinical Scientific Centre
)
Danilov Mikhail Alexandrovich (Head of the Coloproctology Department
Candidate of Medical Sciences (Ph.D.)
A.S. Loginov Moscow Clinical Scientific Centre
)
Knyazev Oleg Vladimirovich (Head of the Intestinal Pathology Department
Doctor of Medical Sciences (M.D.), Professor
A.S. Loginov Moscow Clinical Scientific Centre
)
Tsvirkun Viktor Viktorovich (Chief Research Scientist
Doctor of Medical Sciences (M.D.), Professor
A.S. Loginov Moscow Clinical Scientific Centre
)
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The issues of diagnosis and timely treatment, including surgical intervention, of colitis of various etiologies are becoming increasingly relevant today. A wide range of nosological entities can be concealed behind the clinical presentation of acute colitis. Among all types of colitis, ulcerative colitis (UC), pseudomembranous colitis (PMC), and ischemic colitis (IC) have gained the greatest socio-economic significance in the post-COVID era. UC and PMC are diseases in which the inflammatory component plays a major role in disease progression, whereas IC is primarily driven by ischemic mechanisms. Before the development of severe and rapidly progressive (fulminant) complicated forms of colitis, a specific range of etiopathogenetic factors leads to significant differences in the clinical presentation of these conditions, necessitating a personalized approach to the application of various treatment algorithms. These approaches are well studied and described in international clinical guidelines. However, in severe and fulminant forms of UC, PMC, and IC, the inflammatory and ischemic components gradually become nearly identical. This convergence results in a similar clinical presentation of colitis in its terminal stages. Currently, no systematic comparative studies analyzing all three nosological entities exist.
Keywords:fulminant colitis, ulcerative colitis, pseudomembranous colitis, ischemic colitis, ineffectiveness of conservative therapy, risk factors for surgical intervention.
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Read the full article …
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Citation link:
Krotov G. A., Danilov M. A., Knyazev O. V., Tsvirkun V. V. MANAGEMENT FEATURES OF PATIENTS WITH FULMINANT COLITIS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2025. -№04. -С. 230-236 DOI 10.37882/2223-2966.2025.04.25 |
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