Kapralov Sergey Vladimirovich (Doctor of Medicine Sciences, associate professor, Head of the Department of Faculty Surgery and Oncology, Saratov State Medical University named after V.I. Razumovsky)
Polidanov Maxim Andreevich (research department specialist, assistant of the Department of Biomedical Disciplines, University «Reaviz», Saint Petersburg, Russian Federation)
Petrunkin Rodion Pavlovich (Private University «Reaviz», Saint Petersburg, Russia)
Kashikhin Andrey Andreevich (Private University «Reaviz», Saint Petersburg, Russia)
Volkov Kirill Andreevich (Saratov State Medical University named after V.I. Razumovsky, Saratov, Russian Federation)
Maslyakov Vladimir Vladimirovich (Doctor of Medical Sciences, Professor of the Department of Mobilization Preparation of Public Health and Disaster Medicine, Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia; Doctor of Medical Sciences, Professor, Professor of the Department of Surgical Diseases, Medical University «Reaviz», Saratov, Russia)
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The aim of the study is to experimentally substantiate a new method of modeling the mine-axillary action of soft tissue and pelvic organ trauma in laboratory animals. Materials and Methods. The studies were carried out on 20 female laboratory rats of “Standard” breed weighing 200±50 g. Results of the study. It was found out that the mine-shrapnel injuries received with the use of the developed method in all experimental animals were identical by the nature and severity of soft tissue injuries, their localization, shape, area and depth. In each laboratory animal there was a complete rupture of the uterine wall with its separation from the ligaments and from the aponeurosis of Denon-Willier, limiting the vagina from the rectum. Morphologic evaluation performed during the experiment allowed to establish that the edges of the rupture were uneven, with signs of smearing and hemorrhage. In the surrounding tissue there was pronounced acute inflammation with a large number of bacillary leukocytes and observed foci of coagulation necrosis. Conclusions. Thus, the obtained experimental data confirm that the developed method provides obtaining of reproducible model of mine- and fragmentation-directed trauma action, will allow to use it for modeling of lesions corresponding to mine- and fragmentation-directed trauma action (by shock wave and damage by impacting fragments) of soft tissues and pelvic organs in rats.
Keywords:Mortar fragmentation injury, strikeball grenade, experimental modeling, female rats.
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Citation link:
Kapralov S. V., Polidanov M. A., Petrunkin R. P., Kashikhin A. A., Volkov K. A., Maslyakov V. V. EXPERIMENTAL SUBSTANTIATION OF MODELING OF MINE AND SHRAPNEL DIRECTED TRAUMA OF SOFT TISSUES AND PELVIC ORGANS IN LABORATORY ANIMALS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2025. -№04. -С. 215-219 DOI 10.37882/2223-2966.2025.04.20 |
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