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CHANGES IN ENDOTHELIUM-DEPENDENT VASODILATION (EDVD) IN PATIENTS WITH ISCHEMIC HEART DISEASE (IHD) AGAINST THE BACKGROUND OF A TRANSFERRED NEW CORONAVIRUS INFECTION (COVID-19)

Bolgov Daniil Yurievich  (cardiologist, BUZ VO VOKB № 1, Voronezh )

Kuznetsov Dmitry Sergeevich  (cardiologist, BUZ VO VOKB № 1, Voronezh )

Kuznetsov Sergey Ivanovich  (MD, Professor, Voronezh State Medical University named after N.N.Burdenko Ministry of Health of the Russian Federation, Voronezh)

Muradyan Irina Fedorovna  (resident physician, Voronezh State Medical University named after N.N.Burdenko Ministry of Health of the Russian Federation, Voronezh )

The article formulates a modern understanding of endothelial dysfunction and methods for its assessment. In the course of the work, the dynamics of indicators characterizing endothelial damage are considered. Using the example of the endothelium-dependent vasodilation (EDVD) test of the brachial artery, the study of the functional state of the endothelium is presented, which underlies the change in the diameter of the brachial artery using a high-resolution ultrasound device. Endothelial dysfunction is considered one of the main links in the pathogenesis of complications after a transferred new coronavirus infection. It was noted that endothelial dysfunction mainly occurs in elderly patients who may have comorbid pathology. The authors conclude that to increase the duration and quality of life of patients with ischemic heart disease (IHD), especially those who have transferred the new coronavirus infection COVID-19, to reduce the risk and frequency of complications, mortality indicators, it is necessary to study the endothelial function in more detail. Ways to seek drug treatment for endothelial dysfunction should be sought, taking into account the pathogenetic mechanisms of its formation.

Keywords:endothelial dysfunction, endothelium-dependent vasodilation (EDVD), endothelial damage, ischemic heart disease (IHD), COVID-19
 

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Citation link:
Bolgov D. Y., Kuznetsov D. S., Kuznetsov S. I., Muradyan I. F. CHANGES IN ENDOTHELIUM-DEPENDENT VASODILATION (EDVD) IN PATIENTS WITH ISCHEMIC HEART DISEASE (IHD) AGAINST THE BACKGROUND OF A TRANSFERRED NEW CORONAVIRUS INFECTION (COVID-19) // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2026. -№01. -С. 195-198 DOI 10.37882/2223-2966.2026.01.10
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