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HYPERPROLACTINEMIA AS A CAUSE OF INFERTILE MARRIAGE: MODERN CONCEPTS

Tarasova Irina Dmitrievna  (Obstetrician-gynecologist, endocrinologist Professor Kalinchenko Clinic LLC, Moscow, Russia )

Kalinchenko Svetlana Yurievna  (MD, Professor Patrice Lumumba Peoples' Friendship University of Russia, Moscow, Russia )

Vorslov Leonid Olegovich  (Candidate of Medical Sciences, Associate Professor, Patrice Lumumba Peoples' Friendship University of Russia, Moscow, Russia )

Kononova Valeria Igorevna  (Resident physician, Patrice Lumumba Peoples' Friendship University of Russia, Moscow, Russia )

Grigoriev Nikolay Nikolaevich  (Endocrinologist, urologist, andrologist Delta LLC )

Hyperprolactinemia is one of the most common endocrine causes of infertile marriage, affecting ovulation, implantation, and spermatogenesis. The review presents current data on the pathogenesis and clinical manifestations of hyperprolactinemia, methods of its diagnosis, including assessment of biologically active forms of prolactin and neuroimaging. The influence of hyperprolactinemia on the probability of pregnancy, the frequency of reproductive losses and perinatal outcomes is considered. An analysis of the literature confirms that timely diagnosis and individualized therapy can significantly increase the likelihood of pregnancy and successful completion in women, as well as improve spermatogenesis in men. The need for an interdisciplinary approach to patient management and the prospects for further research in the field of personalized medicine, including the study of the role of nutritional factors, are emphasized.

Keywords:hyperprolactinemia, infertile marriage, prolactin, prolactinoma, reproductive function, anovulation, spermatogenesis, dopamine agonists, macroprolactinemia, Omega-3 index.

 

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Citation link:
Tarasova I. D., Kalinchenko S. Y., Vorslov L. O., Kononova V. I., Grigoriev N. N. HYPERPROLACTINEMIA AS A CAUSE OF INFERTILE MARRIAGE: MODERN CONCEPTS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2026. -№02/2. -С. 198-205 DOI 10.37882/2223-2966.2026.02-2.23
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