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EFFICACY OF PLATELET-RICH PLASMA APPLICATION IN THE TREATMENT OF TIBIAL NONUNION

Kesyan Gurgen Abavenovich  (Doctor of Medical Sciences, Traumatologist-orthopedist, Head of the 8th Traumatology and Orthopedic Department, Federal State Budgetary Institution "N.N. Priorov National Medical Research Center of Traumatology and Orthopedics)

Kesyan Ovsep Gurgenovich  (Candidate of Medical Sciences, Traumatologist-orthopedist, Senior Researcher, Federal State Budgetary Institution "N.N. Priorov National Medical Research Center of Traumatology and Orthopedics")

Latyrova Tamara Tagirovna  (Intern, Traumatologist-orthopedist, Resident, Federal State Budgetary Institution "N.N. Priorov National Medical Research Center of Traumatology and Orthopedics")

Urazgildeev Rashid Zagidullovich  (Doctor of Medical Sciences, Traumatologist-orthopedist, Leading Researcher, Federal State Budgetary Institution "N.N. N. N. Priorov")

Karapetyan Grigory Sergeevich  (Candidate of Medical Sciences, Traumatologist-orthopedist, Federal State Budgetary Institution "N. N. Priorov National Medical Research Center of Traumatology and Orthopedics")

Arsenyev Igor Gennadievich  (Candidate of Medical Sciences, Traumatologist-orthopedist, Federal State Budgetary Institution "N. N. Priorov National Medical Research Center of Traumatology and Orthopedics")

Vanyan Eduard Sergeevich  (Postgraduate student, Federal State Budgetary Institution "N. N. Priorov National Medical Research Center of Traumatology and Orthopedics")

Pashkov Feodor Sergeevich  (Postgraduate student, Federal State Budgetary Institution "N. N. Priorov National Medical Research Center of Traumatology and Orthopedics")

Tibial nonunion is a severe orthopedic condition characterized by impaired fracture healing and a significant decline in patients' quality of life. This study evaluates the effectiveness of platelet-rich plasma (PRP) application in treating post-traumatic tibial nonunion. A total of 52 patients were included in the study, divided into two groups: the PRP-treated group and the control group. Assessment was based on radiographic findings, clinical indicators, and functional outcomes. The analysis demonstrated that PRP significantly accelerates bone healing, reduces consolidation time, and promotes functional recovery. However, no statistically significant differences in long-term functional outcomes were observed between the groups. The study confirms the feasibility of using PRP as an adjunctive method in the complex treatment of nonunions, enhancing bone regeneration processes.

Keywords:Nonunion, tibial fracture, platelet-rich plasma, PRP, bone regeneration, orthopedic surgery, osteosynthesis methods

 

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Citation link:
Kesyan G. A., Kesyan O. G., Latyrova T. T., Urazgildeev R. Z., Karapetyan G. S., Arsenyev I. G., Vanyan E. S., Pashkov F. S. EFFICACY OF PLATELET-RICH PLASMA APPLICATION IN THE TREATMENT OF TIBIAL NONUNION // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2025. -№04/2. -С. 160-165 DOI 10.37882/2223-2966.2025.04-2.16
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